Fluidized Bed Processing for Multiparticulates
نویسندگان
چکیده
World wide in pharmaceutical industry, fluid bed processing technology emerged as useful application. Batch type fluid processes are using in pharmaceutical industry since 30 years. Originating in Europe, this technology gradually found its way into U.S. manufacturing facilities, beginning with the use of fluid bed dryers. The earliest fluid bed dryers were a cabinet type construction with a simple cylindrical product container which was located on exhaust air filter. Even with such an elementary design, it was apparent that new methods showed great superiority over conventional tray drying techniques. This attracted a great deal of interest within the pharmaceutical industry which leads to improvements in the design and additional features were soon developed. This gave rise to applications other than drying of granules like spray agglomeration, coating of spheroids, particle coating and powder coating. Now fluid bed process technology plays a wonderful instruments /machines to manufacture and coating of multiparticulates.
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